Grant Patents

SENSOGRAM TECHNOLOGIES, INC.

1. Methods and Devices for Non-Invasively Measuring Quantitative Information of Substances in Living Organisms

Patent number: 7,395,104

Abstract: Disclosed are systems and methods of determining the amount of a substance in a living organism. In one embodiment, the method comprises: applying an electrical signature signal to the living organism, wherein the electrical signature signal corresponds to a predetermined amount of the substance; measuring the response of the living organism to the applied signature signal; and determining whether an elevated response has resulted from applying the electrical signature signal, if so, then determining the amount of the substance in the living organism from the predetermined amount of the substance.

Type: Grant

Filed: March 6, 2005

Date of Patent: July 1, 2008

Assignee: Sensogram Technologies, Inc.

Inventors: Vahram Mouradian, Valeri Armenakyan, Maksim Malkin, Gagik Farmanyan, Minas Hambardzumyan

Value Proposition: This is the system allowing measuring various bio-chemical substances in the physiological system, not just of human, but also of any living organisms. The prototype using this patent has been a non-invasive (in-vitro) blood glucose monitoring system. Second example prototype has been designed for the identification of heavy metals in the human body. Extensive clinical data was obtained in identification of various bacteria and viruses in the mammals. The main principal being the Bio-Impedance Spectroscopy this patent matter and instruments built on the principals of this invention may allow performing in-vitro bio-chemical analysis potentially and partially replacing in-vivo bio-chemical tests. The patent is granted and issued in the USA, Canada, EU and PCT. Potential usability of the method and apparatus described in the patent in the order of priority addressing different market verticals from the largest to the les significant could be: 1. Non-invasive blood glucose monitor; 2. Non-invasive bacteria presence identification in the human body; 3. Non-invasive virus presence identification in the human body; 4. Non-invasive heavy metals presence identification in the human body.


2. Ear scanner

Patent number: D808,018

Abstract: Disclosed is a design system wearable in the human ear shell without plugging the ear-hole. The significance of the disclosed design in its ability to hold steadily in the ear-shell and fit practically in any size of the ear while maintaining the touch to the inside of the ear-shell allowing the optical sensor to read the blood flow from the passing underneath of the ear artery. Directional speaker built in the Ear Scanner allows the audio interface of the device with the user in an interactive manner. It has a built-in Bluetooth transmitter allowing the Ear Scanner to communicate with the nearby Bluetooth hub such as a phone, tablet, and/or a Bluetooth hub. In another embodiment instead of a Bluetooth communication could be other communication method such as Zigbee, or ANT+, or others. Ear Scanner has a built-in rechargeable battery pack.

Type: Grant

Filed: May 3, 2015

Date of Patent: January 16, 2018

Assignee: Sensogram Technologies, Inc.

Inventors: Vahram Mouradian, Boris Melikyan

Value Proposition: With the growing market in both consumer and medical wearable devices the form factor allowing accommodate a wealth of functionality, ease of interface, convenience of wearing, while making it a reliable and cost effective piece, becomes the most important aspect in the design of apparatus of the device. Ear form factor goes in competition with the wristwatch, ring, chest-belt, and other form factors. Advantages of the ear scanner are: 1. Hands-free interface through the audio, such as communicating the vitals, alerting certain thresholds of achieved parameters, report alerts of coming from vitals’ analysis; 2. Ability to entertain and play music while monitoring various physiological parameters; 3. Ability to read hemodynamics of the vascular system from the close proximity to the heart (head versus wrist or fingers) from the short circulation of the blood in the head. Ear Scanner has a unique design allowing the user to wear it easily on the ear. Having such a solution for deployment of any integrated sensor on the head/ear of the human allows utilization of various innovative technologies in a uniquely convenient form-factor. Various solutions in the Ear Scanner such as the ear-shell holding piece, such as the ear-hole opened speaker system, motion-invariant clipping system withholding any movement of the user, lightweight and slick design, trendy colors, all these give Ear Scanner a strong competitive edge to wrist-worn devices, to finger-worn devices, to chest straps and arm-bands. This could be the next frontier in integrated hands-free monitoring and entertainment combo solution.


3. Apparatus for ambient noise cancellation in PPG sensors

Patent number: 9,936,885

Abstract: Disclosed is a PPG signal measurement apparatus comprising a light source for emitting light pulses; a light sensor for receiving reflected light from the light source and generating a sensor signal; an electronic unit including a transimpedance amplifier and an ambient light cancelation unit, a first switch in a front end portion of the light sensor, a second switch in the front end portion of the light sensor, a microcontroller in communication with the light source, the light sensor, and the ambient light cancellation unit.

Type: Grant

Filed: March 31, 2015

Date of Patent: April 10, 2018

Assignee: Sensogram Technologies, Inc.

Inventors: Vahram Mouradian, Levon Hovhannisyan, Armen Poghosyan

Value Proposition: With the popularity of Photoplethysmogramic wearable sensors several industries start using these non-expensive and well accommodating optical devices as part of their sensing devices to read the tissues non-invasively. PPG sensor is simply being a combination of a light source (LED) and a light-sensing element (photo detector) is the sensing device in Fitbit, Garmin, etc. For example, heart rate monitors all has a PPG sensor in them. The mentioned demand created a spike in massive production of PPG sensors by electronic component manufacturers such as OSRAM, Texas Instrument, Maxim, etc. One of the obstacles in using the PPG sensor is the fact of the ambient light interfering with the LED light causing the sensor malfunction. This patent is offering a solution implemented in a form of a method and apparatus to control the switching timing of different components of the sensor (LED, photo detector). Virtually costing nothing to implement the patented technology, every sensor in the world can use it. As a matter of fact, several companies are using indeed this patented technology/methodology. Not only has this interest has been mainly encouraged by the rapid demand growth in the wearable technology market for the ubiquitous, continuous, and pervasive monitoring of vital signs, but it has been leveraged by the state-of-the-art technological developments in sensor technology and wireless communications. The wearable technology market was valued at over $13.2 billion by the end of 2016 and its value is forecast to reach $34 billion by the end of 2020. Any type of PPG sensor is or can use this patented technology to be operational in the presence of the ambient light such as a natural daylight, such as any artificial lighting fixtures.


4. Wearable sensor ring

Patent number: D820,124

Type: Grant

Filed: February 20, 2017

Date of Patent: June 12, 2018

Assignee: Sensogram Technologies, Inc.

Inventors: Vahram Mouradian

Value Proposition: This is a design patent for a wearable form factor of a finger-worn ring. Wearable Sensor Ring design patents have been filed and issued in China and Europe as well. Any finger-worn wearable device, which ha s a sensor in it potentially may fall in the category of a wearable sensor ring thus potentially infringing this patent. The design of the Ring is specific to accommodate multiple finger sizes while still meeting the requirements for such a sensing ring. These requirements are meant to satisfy the user comfort and experience while allowing the physics of optical, electrical, motion and temperature sensing apply and work. Various derivative form factors from this patented ring will be filed in the near future to meet the demand of continuous innovation in this form factor we as a company are after. In the event of a wearable ring development this patent is extremely useful and will give the user initial strong position to not be worry about all the details which are specific for such a wearable device. It accommodates such properties as: long comfortable wearing, multiple sizes coverage between 16mm and 24mm millimeters of a finger diameter, allows to access the top electrode with the other hands fingers thus allowing to make an ECG reading, ability to house optical sensor with the heat dissipation profile compliant with the standards requirements, ease of putting it on the finger and taking off, sufficient sturdiness and meantime softness on the skin. It has a built-in two electrical contacts, a cavity for the electronic flex-board, optical sensor set, temperature sensor set, and for a rechargeable battery. In the design of the Ring ergonomics and functional ability are merged delivering a ready-to-use enclosure with well-thought integrated sensor consideration. One of the unique properties of the Wearable Sensor Ring is the used material for the sturdy upper part of the enclosure or the ‘shell’, which is made of a plastic alloy, which keeps the same tension on the finger regardless of its size. As a new and interesting form factor for the wearable technology implementation on the humans where one of the major data is the photoplethystogram, disclosed enclosure has all necessary properties to accommodate the PPG reading, including but not limited to the optical transparency of the materials, form factor accommodating fingers’ multiple sizes, materials allowing continuous wearing on any finger of either hand without causing it to sweat, be squeezed, or irritated (anatomical and biocompatibility). Disclosed design has gone Design for Manufacturability (DFM), Design for Testability (DFT) and Design for Automation (DFA).


5. Continuous non-invasive wearable blood pressure monitoring system

Patent number: 10,117,586

Abstract: Presented are embodiments of an apparatus and methodology integrated in the system for non-invasive, continuous, wearable, remote and mobile monitoring of human blood pressure by photoplethysmography (PPG) based sensor and an electronic processing unit with the embedded radio allowing the reading and transmittal of the read blood pressure data to the remote location.

Type: Grant

Filed: March 31, 2015

Date of Patent: November 6, 2018

Assignee: Sensogram Technologies, Inc.

Inventors: Vahram Mouradian, Armen Poghosyan


6. Non-invasive wearable respiration rate monitoring system

Patent number: 10,117,598

Abstract: There is disclosed a respiration rate monitoring system and method using a non-invasive device and method of monitoring it nearly continuously. One aspect includes receiving a series of signal data points from an optical sensor, detecting a series of peaks or valleys for the filtered signal data points, determining the time difference between individual peaks or valleys of the series of peaks or valleys to produce a series of time difference values, detecting peaks or valleys for the series of time difference values, determining widths between the peaks or valleys of the series of time difference values, and estimating a respiration rate from the widths between the peaks or valleys of the series of time difference values, and converting the estimation of a respiration rate to an indicator indicative of a respiration rate.

Type: Grant

Filed: November 4, 2016

Date of Patent: November 6, 2018

Assignee: Sensogram Technologies, Inc.

Inventors: Vahram Mouradian


7. Finger Tip Scanner

Patent number: D839,270

Type: Grant

Filed: May 3, 2015

Date of Patent: January 29, 2019

Assignee: Sensogram Technologies, Inc.

Inventors: Vahram Mouradian, Boris Melikyan

Value Proposition: This is a design patent for a wearable form factor of a finger-worn clip. Finger Tip Scanner design patent have been filed and issued in the USA only. Any finger-tip-worn wearable device, which has a sensor in it potentially may fall in the category of a finger tip scanner thus potentially infringing this patent subject to the design claim. The design of this patented Scanner is specific to accommodate multiple finger sizes while having a steady pressure on the finger in the expected force limits, regardless on the finger size. These requirements are meant to satisfy the user comfort and experience while allowing the physics of optical, electrical, motion and temperature sensing apply and work. Various derivative form factors from this patented scanner will be filed in the near future to meet the demand of continuous innovation in this form factor which Sensogram is after. In the event of a wearable scanner development with the specifics of this design and its properties, this patent is extremely useful and will give the user initial strong position to not be worry about all the details which are specific for such a wearable device. It accommodates such properties as: long comfortable wearing, multiple sizes of a finger diameter, ability to house optical sensor with the heat dissipation profile compliant with the standards requirements, ease of putting it on the finger and taking off, sufficient sturdiness and meantime softness on the skin. It has a cavity for the electronic flex-board, optical sensor set, temperature sensor set, and for a rechargeable battery. In the design of the Scanner ergonomics and functional ability are merged delivering a ready-to-use enclosure with well-thought integrated sensor consideration. One of the unique properties of the Finger Tip Scanner is the used material for the sturdy upper part of the enclosure or the ‘shell’, which is made of a plastic alloy, which keeps the same tension on the finger regardless of its size. As a new and interesting form factor for the wearable technology implementation on the humans where one of the major data is the photoplethysmogram, disclosed enclosure has all necessary properties to accommodate the PPG reading, including but not limited to the optical transparency of the materials, form factor accommodating fingers’ multiple sizes, materials allowing continuous wearing on any finger of either hand without causing it to sweat, be squeezed, or irritated (anatomical and biocompatibility). Disclosed design has gone Design for Manufacturability (DFM), Design for Testability (DFT) and Design for Automation (DFA).

Applications

8. Integrated Biosensor

Patent number: 2018/0235483

Abstract: A biosensor device having a housing having an inner surface, a band extending from the housing and configured to enclose an attachment site on a user's body, and a sensor package. The sensor package includes at least one optical emitter oriented to selectively emit a respective first light from the inner surface, and a plurality of optical receivers surrounding the at least one optical emitter and configured to receive reflected light at the inner surface.

Type: Application

Filed: February 15, 2018

Date of Patent: August 23, 2018

Assignee: Sensogram Technologies, Inc.

Inventors: Vahram Mouradian


9. Photoplethysmographic Wearable Blood Pressure Monitoring System and Methods

Patent number: 2018/0235489

Abstract: A photoplethysmographic (“PPG”) device having a housing, a band and a first optical sensor. The band extends from the housing and is configured to enclose an attachment site on a user's body. The PPG device has an inner surface oriented to face the attachment site and an outer surface oriented to face away from the attachment site. The first optical sensor includes at least one first optical emitter oriented to selectively emit a respective first light from the outer surface, and at least one first optical receiver oriented to receive a reflected portion of the respective first light returning to the outer surface. The respective first light is selected from one or more wavelengths operative to reflect from one or more of oxyhemoglobin and deoxyhemoglobin at an observation site on the user's body, the observation site being remote from the attachment site.

Type: Application

Filed: February 15, 2018

Date of Patent: August 23, 2018

Assignee: Sensogram Technologies, Inc.

Inventors: Vahram Mouradian, Armen Poghosyan


10. Photoplethysmographic Wearable Blood Pressure Monitoring System and Methods (WO)

Patent number: 2018/102486

Abstract: A method for estimating blood pressure, including: identification of representative PPG pulse curve shapes associated with first and second direct non-invasive blood pressure measurements; generation of at least one blood pressure correlation function representing at least a relationship between a first difference between the first shape and the second shape, and a second difference between the first direct blood pressure measurement and the second direct blood pressure measurement; obtaining a measured PPG pulse signal from a patient; identifying a measured representative shape of a measured PPG pulse curve from the measured PPG pulse signal; and generating an estimated blood pressure based on the measured representative shape and the at least one blood pressure correlation function.

Type: International Application

Filed: November 30, 2017

Date of Patent: June 7, 2018

Assignee: Sensogram Technologies, Inc.

Inventors: Vahram Mouradian


11. Fall Sensing and Medical Alert Systems

Patent number: 62/565431

Abstract: The invention generally relates to wearable biosensors for detecting vital signs of the person wearing the device, sensing the body fall of the wearer, and initiate an active alert to the preset parties delivering the location, physiological condition and the state of position of the user.

Type: Application

Filed: November 30, 2017

Date of Patent: September 29, 2017

Assignee: Pending

Inventors: Vahram Mouradian

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